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Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A
The phosphatases PP1 and PP2A are responsible for the majority of dephosphorylation reactions on phosphoserine (pSer) and phosphothreonine (pThr), and are involved in virtually all cellular processes and numerous diseases. The catalytic subunits exist in cells in form of holoenzymes, which impart su...
Autores principales: | Hoermann, Bernhard, Kokot, Thomas, Helm, Dominic, Heinzlmeir, Stephanie, Chojnacki, Jeremy E., Schubert, Thomas, Ludwig, Christina, Berteotti, Anna, Kurzawa, Nils, Kuster, Bernhard, Savitski, Mikhail M., Köhn, Maja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367873/ https://www.ncbi.nlm.nih.gov/pubmed/32681005 http://dx.doi.org/10.1038/s41467-020-17334-x |
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