Ribosome profiling reveals a functional role for autophagy in mRNA translational control

Autophagy promotes protein degradation, and therefore has been proposed to maintain amino acid pools to sustain protein synthesis during metabolic stress. To date, how autophagy influences the protein synthesis landscape in mammalian cells remains unclear. Here, we utilize ribosome profiling to deli...

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Detalles Bibliográficos
Autores principales: Goldsmith, Juliet, Marsh, Timothy, Asthana, Saurabh, Leidal, Andrew M., Suresh, Deepthisri, Olshen, Adam, Debnath, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367890/
https://www.ncbi.nlm.nih.gov/pubmed/32681145
http://dx.doi.org/10.1038/s42003-020-1090-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367890/
https://www.ncbi.nlm.nih.gov/pubmed/32681145
http://dx.doi.org/10.1038/s42003-020-1090-2

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