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Ribosome profiling reveals a functional role for autophagy in mRNA translational control
Autophagy promotes protein degradation, and therefore has been proposed to maintain amino acid pools to sustain protein synthesis during metabolic stress. To date, how autophagy influences the protein synthesis landscape in mammalian cells remains unclear. Here, we utilize ribosome profiling to deli...
Autores principales: | Goldsmith, Juliet, Marsh, Timothy, Asthana, Saurabh, Leidal, Andrew M., Suresh, Deepthisri, Olshen, Adam, Debnath, Jayanta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367890/ https://www.ncbi.nlm.nih.gov/pubmed/32681145 http://dx.doi.org/10.1038/s42003-020-1090-2 |
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