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Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity: how to evaluate the risk of the S-EDCs?

Theoretically, both synthetic endocrine disrupting chemicals (S-EDCs) and natural (exogenous and endogenous) endocrine disrupting chemicals (N-EDCs) can interact with endocrine receptors and disturb hormonal balance. However, compared to endogenous hormones, S-EDCs are only weak partial agonists wit...

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Detalles Bibliográficos
Autores principales: Autrup, Herman, Barile, Frank A., Berry, Sir Colin, Blaauboer, Bas J., Boobis, Alan, Bolt, Herrmann, Borgert, Christopher J., Dekant, Wolfgang, Dietrich, Daniel, Domingo, Jose L., Gori, Gio Batta, Greim, Helmut, Hengstler, Jan, Kacew, Sam, Marquardt, Hans, Pelkonen, Olavi, Savolainen, Kai, Heslop-Harrison, Pat, Vermeulen, Nico P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367909/
https://www.ncbi.nlm.nih.gov/pubmed/32514609
http://dx.doi.org/10.1007/s00204-020-02800-8

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