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Management Strategies of Acute Retinal Necrosis: Current Perspectives

Acute retinal necrosis is a rare yet devastating disease, with significant ocular morbidity. Over the past several decades, initial treatment regimens have shifted from intravenous antivirals requiring hospital admission to the routine use of oral antivirals with intravitreal antivirals for immediat...

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Detalles Bibliográficos
Autores principales: Powell, Brittany, Wang, Daniel, Llop, Stephanie, Rosen, Richard B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367936/
https://www.ncbi.nlm.nih.gov/pubmed/32764860
http://dx.doi.org/10.2147/OPTH.S258488
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author Powell, Brittany
Wang, Daniel
Llop, Stephanie
Rosen, Richard B
author_facet Powell, Brittany
Wang, Daniel
Llop, Stephanie
Rosen, Richard B
author_sort Powell, Brittany
collection PubMed
description Acute retinal necrosis is a rare yet devastating disease, with significant ocular morbidity. Over the past several decades, initial treatment regimens have shifted from intravenous antivirals requiring hospital admission to the routine use of oral antivirals with intravitreal antivirals for immediate local control. Given the rarity of this disease process and a lack of large-scale research trials, debate continues over recommended practice guidelines. In this paper, we review current diagnostic criteria and recommend a treatment algorithm based on available evidence.
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spelling pubmed-73679362020-08-05 Management Strategies of Acute Retinal Necrosis: Current Perspectives Powell, Brittany Wang, Daniel Llop, Stephanie Rosen, Richard B Clin Ophthalmol Review Acute retinal necrosis is a rare yet devastating disease, with significant ocular morbidity. Over the past several decades, initial treatment regimens have shifted from intravenous antivirals requiring hospital admission to the routine use of oral antivirals with intravitreal antivirals for immediate local control. Given the rarity of this disease process and a lack of large-scale research trials, debate continues over recommended practice guidelines. In this paper, we review current diagnostic criteria and recommend a treatment algorithm based on available evidence. Dove 2020-07-08 /pmc/articles/PMC7367936/ /pubmed/32764860 http://dx.doi.org/10.2147/OPTH.S258488 Text en © 2020 Powell et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Powell, Brittany
Wang, Daniel
Llop, Stephanie
Rosen, Richard B
Management Strategies of Acute Retinal Necrosis: Current Perspectives
title Management Strategies of Acute Retinal Necrosis: Current Perspectives
title_full Management Strategies of Acute Retinal Necrosis: Current Perspectives
title_fullStr Management Strategies of Acute Retinal Necrosis: Current Perspectives
title_full_unstemmed Management Strategies of Acute Retinal Necrosis: Current Perspectives
title_short Management Strategies of Acute Retinal Necrosis: Current Perspectives
title_sort management strategies of acute retinal necrosis: current perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367936/
https://www.ncbi.nlm.nih.gov/pubmed/32764860
http://dx.doi.org/10.2147/OPTH.S258488
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