Global translation during early development depends on the essential transcription factor PRDM10

Members of the PR/SET domain-containing (PRDM) family of zinc finger transcriptional regulators play diverse developmental roles. PRDM10 is a yet uncharacterized family member, and its function in vivo is unknown. Here, we report an essential requirement for PRDM10 in pre-implantation embryos and em...

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Detalles Bibliográficos
Autores principales: Han, Brenda Y., Seah, Michelle K. Y., Brooks, Imogen R., Quek, Delia H. P., Huxley, Dominic R., Foo, Chuan-Sheng, Lee, Li Ting, Wollmann, Heike, Guo, Huili, Messerschmidt, Daniel M., Guccione, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368010/
https://www.ncbi.nlm.nih.gov/pubmed/32681107
http://dx.doi.org/10.1038/s41467-020-17304-3

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