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MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

TRIM family proteins play integral roles in the innate immune response to virus infection. MG53 (TRIM72) is essential for cell membrane repair and is believed to be a muscle-specific TRIM protein. Here we show human macrophages express MG53, and MG53 protein expression is reduced following virus inf...

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Detalles Bibliográficos
Autores principales:	Sermersheim, Matthew, Kenney, Adam D., Lin, Pei-Hui, McMichael, Temet M., Cai, Chuanxi, Gumpper, Kristyn, Adesanya, T. M. Ayodele, Li, Haichang, Zhou, Xinyu, Park, Ki-Ho, Yount, Jacob S., Ma, Jianjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368064/ https://www.ncbi.nlm.nih.gov/pubmed/32681036 http://dx.doi.org/10.1038/s41467-020-17177-6

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