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Effect of Inhaled Cannabis for Pain in Adults With Sickle Cell Disease: A Randomized Clinical Trial
IMPORTANCE: Sickle cell disease (SCD) is characterized by chronic pain and episodic acute pain caused by vasoocclusive crises, often requiring high doses of opioids for prolonged periods. In humanized mouse models of SCD, a synthetic cannabinoid has been found to attenuate both chronic and acute hyp...
Autores principales: | Abrams, Donald I., Couey, Paul, Dixit, Niharika, Sagi, Varun, Hagar, Ward, Vichinsky, Elliott, Kelly, Mary Ellen, Connett, John E., Gupta, Kalpna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368173/ https://www.ncbi.nlm.nih.gov/pubmed/32678452 http://dx.doi.org/10.1001/jamanetworkopen.2020.10874 |
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