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Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation in Patients with a History of Keratoplasty
PURPOSE: To examine the surgical outcomes and graft conditions in patients receiving micropulse transscleral cyclophotocoagulation (MP-TSCPC) to treat post-keratoplasty ocular hypertension. METHODS: This retrospective observational study included 30 eyes of 28 consecutive glaucoma patients with a hi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368213/ https://www.ncbi.nlm.nih.gov/pubmed/32695499 http://dx.doi.org/10.1155/2020/6147248 |
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author | Lee, Jun Hui Vu, Vivian Lazcano-Gomez, Gabriel Han, Katherine Suvannachart, Pukkapol Rose-Nussbaumer, Jennifer Schallhorn, Julie Hwang, David Han, Ying |
author_facet | Lee, Jun Hui Vu, Vivian Lazcano-Gomez, Gabriel Han, Katherine Suvannachart, Pukkapol Rose-Nussbaumer, Jennifer Schallhorn, Julie Hwang, David Han, Ying |
author_sort | Lee, Jun Hui |
collection | PubMed |
description | PURPOSE: To examine the surgical outcomes and graft conditions in patients receiving micropulse transscleral cyclophotocoagulation (MP-TSCPC) to treat post-keratoplasty ocular hypertension. METHODS: This retrospective observational study included 30 eyes of 28 consecutive glaucoma patients with a history of penetrating keratoplasty (PKP) or Descemet's stripping automated endothelial keratoplasty (DSAEK) who underwent MP-TSCPC at the University of California, San Francisco from 09/2015 to 08/2018. Using the Wilcoxon signed-rank test, we compared preoperative and postoperative intraocular pressure (IOP), number of glaucoma medications, visual acuity, and central corneal thickness at 1, 3, 6, and 12 months. Postoperative complications, additional surgeries, and graft failures were also recorded at these follow-up times. Linear regression model was used to study whether PKP vs. DSAEK affects the effectiveness of MP-TSCPC. RESULTS: Thirty eyes from 28 patients were followed for 12 months. IOP was significantly decreased from preop at all follow-up points (P < 0.001). There was no significant change in the number of glaucoma drops, visual acuity, or CCT. At 12 months, 21 of the 30 eyes met the definition of success, and only one underwent repeat PKP due to graft rejection. The type of corneal transplant was not a significant factor for IOP reduction at the last follow-up. CONCLUSIONS: MP-TSCPC achieved desirable IOP control and success rates for postkeratoplasty patients while resulting in minimal complications and graft failure. It appears to be a safe and effective procedure in patients who received corneal transplant with one-year follow-up. |
format | Online Article Text |
id | pubmed-7368213 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-73682132020-07-20 Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation in Patients with a History of Keratoplasty Lee, Jun Hui Vu, Vivian Lazcano-Gomez, Gabriel Han, Katherine Suvannachart, Pukkapol Rose-Nussbaumer, Jennifer Schallhorn, Julie Hwang, David Han, Ying J Ophthalmol Research Article PURPOSE: To examine the surgical outcomes and graft conditions in patients receiving micropulse transscleral cyclophotocoagulation (MP-TSCPC) to treat post-keratoplasty ocular hypertension. METHODS: This retrospective observational study included 30 eyes of 28 consecutive glaucoma patients with a history of penetrating keratoplasty (PKP) or Descemet's stripping automated endothelial keratoplasty (DSAEK) who underwent MP-TSCPC at the University of California, San Francisco from 09/2015 to 08/2018. Using the Wilcoxon signed-rank test, we compared preoperative and postoperative intraocular pressure (IOP), number of glaucoma medications, visual acuity, and central corneal thickness at 1, 3, 6, and 12 months. Postoperative complications, additional surgeries, and graft failures were also recorded at these follow-up times. Linear regression model was used to study whether PKP vs. DSAEK affects the effectiveness of MP-TSCPC. RESULTS: Thirty eyes from 28 patients were followed for 12 months. IOP was significantly decreased from preop at all follow-up points (P < 0.001). There was no significant change in the number of glaucoma drops, visual acuity, or CCT. At 12 months, 21 of the 30 eyes met the definition of success, and only one underwent repeat PKP due to graft rejection. The type of corneal transplant was not a significant factor for IOP reduction at the last follow-up. CONCLUSIONS: MP-TSCPC achieved desirable IOP control and success rates for postkeratoplasty patients while resulting in minimal complications and graft failure. It appears to be a safe and effective procedure in patients who received corneal transplant with one-year follow-up. Hindawi 2020-07-09 /pmc/articles/PMC7368213/ /pubmed/32695499 http://dx.doi.org/10.1155/2020/6147248 Text en Copyright © 2020 Jun Hui Lee et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lee, Jun Hui Vu, Vivian Lazcano-Gomez, Gabriel Han, Katherine Suvannachart, Pukkapol Rose-Nussbaumer, Jennifer Schallhorn, Julie Hwang, David Han, Ying Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation in Patients with a History of Keratoplasty |
title | Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation in Patients with a History of Keratoplasty |
title_full | Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation in Patients with a History of Keratoplasty |
title_fullStr | Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation in Patients with a History of Keratoplasty |
title_full_unstemmed | Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation in Patients with a History of Keratoplasty |
title_short | Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation in Patients with a History of Keratoplasty |
title_sort | clinical outcomes of micropulse transscleral cyclophotocoagulation in patients with a history of keratoplasty |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368213/ https://www.ncbi.nlm.nih.gov/pubmed/32695499 http://dx.doi.org/10.1155/2020/6147248 |
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