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Vitamin K for kidney transplant organ recipients: investigating vessel stiffness (ViKTORIES): study rationale and protocol of a randomised controlled trial

BACKGROUND: Renal transplant recipients (RTRs) exhibit increased vascular stiffness and calcification; these parameters are associated with increased cardiovascular risk. Activity of endogenous calcification inhibitors such as matrix gla protein (MGP) is dependent on vitamin K. RTRs commonly have su...

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Detalles Bibliográficos
Autores principales: Lees, Jennifer Susan, Mangion, Kenneth, Rutherford, Elaine, Witham, Miles D, Woodward, Rosemary, Roditi, Giles, Hopkins, Tracey, Brooksbank, Katriona, Jardine, Alan G, Mark, Patrick B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368482/
https://www.ncbi.nlm.nih.gov/pubmed/32675297
http://dx.doi.org/10.1136/openhrt-2019-001070