Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer

BACKGROUND: Radiation therapy (RT) has the potential to enhance the efficacy of immunotherapy, such as checkpoint inhibitors, which has dramatically altered the landscape of treatments for many cancers, but not yet for pancreatic ductal adenocarcinoma (PDAC). Our prior studies demonstrated that PD l...

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Detalles Bibliográficos
Autores principales: Fujiwara, Kenji, Saung, May Tun, Jing, Hao, Herbst, Brian, Zarecki, MacKenzie, Muth, Stephen, Wu, Annie, Bigelow, Elaine, Chen, Linda, Li, Keyu, Jurcak, Neolle, Blair, Alex B, Ding, Ding, Wichroski, Michael, Blum, Jordan, Cheadle, Nathan, Koenitzer, Jennifer, Zheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368549/
https://www.ncbi.nlm.nih.gov/pubmed/32675194
http://dx.doi.org/10.1136/jitc-2019-000351

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