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MicroRNA-27a-3p Reverses Adriamycin Resistance by Targeting BTG2 and Activating PI3K/Akt Pathway in Breast Cancer Cells

AIM: This study aimed to explore the regulative mechanisms of miR-27a-3p in chemo-resistance of breast cancer cells. MATERIALS AND METHODS: qRT-PCR was employed to determine miR-27a-3p expression in two breast cancer cell lines, MCF-7 and MCF-7/adriamycin-resistant cell line (MCF-7/ADR). The two cel...

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Detalles Bibliográficos
Autores principales: Zhu, Bei, Chen, Weixian, Fu, Yue, Cui, Xiaohan, Jin, Lei, Chao, Jiadeng, Yun, Xiao, Gao, Peng, Shan, Shiting, Li, Jun, Yin, Xu, Zhu, Chunfu, Qin, Xihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368588/
https://www.ncbi.nlm.nih.gov/pubmed/32764979
http://dx.doi.org/10.2147/OTT.S256153