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An experimental framework to capture the flow dynamics of droplets expelled by a sneeze
ABSTRACT: Respiratory activities such as sneezing generate pathogen laden droplets that can deposit in the respiratory tract of a susceptible host to initiate infection. The extent of spread of these droplets determines the safe distance between a patient and health care worker. Here, we have presen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368616/ https://www.ncbi.nlm.nih.gov/pubmed/32834458 http://dx.doi.org/10.1007/s00348-020-03008-3 |
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author | Bahl, Prateek de Silva, Charitha M. Chughtai, Abrar Ahmad MacIntyre, C. Raina Doolan, Con |
author_facet | Bahl, Prateek de Silva, Charitha M. Chughtai, Abrar Ahmad MacIntyre, C. Raina Doolan, Con |
author_sort | Bahl, Prateek |
collection | PubMed |
description | ABSTRACT: Respiratory activities such as sneezing generate pathogen laden droplets that can deposit in the respiratory tract of a susceptible host to initiate infection. The extent of spread of these droplets determines the safe distance between a patient and health care worker. Here, we have presented a method to visualize the droplets expelled by a sneeze using light-sheet illumination. This method of visualization provides images that clearly resolve the velocities of droplets with minimal overlapping trajectories, towards understanding their flow dynamics. Furthermore, we present the image processing techniques required to perform accurate Particle Tracking Velocimetry to understand the motion of expelled droplets. Flow fields are presented from applying this methodology over multiple sneezes which reveal that less than 1% of droplets expelled travel at velocities greater than 10 m/s and almost 80% of droplets travel at velocities less than 5 m/s. Furthermore, we observe that some droplets are generated by ligament breakup outside the mouth and some are generated within the respiratory tract. GRAPHIC ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-7368616 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-73686162020-07-20 An experimental framework to capture the flow dynamics of droplets expelled by a sneeze Bahl, Prateek de Silva, Charitha M. Chughtai, Abrar Ahmad MacIntyre, C. Raina Doolan, Con Exp Fluids Research Article ABSTRACT: Respiratory activities such as sneezing generate pathogen laden droplets that can deposit in the respiratory tract of a susceptible host to initiate infection. The extent of spread of these droplets determines the safe distance between a patient and health care worker. Here, we have presented a method to visualize the droplets expelled by a sneeze using light-sheet illumination. This method of visualization provides images that clearly resolve the velocities of droplets with minimal overlapping trajectories, towards understanding their flow dynamics. Furthermore, we present the image processing techniques required to perform accurate Particle Tracking Velocimetry to understand the motion of expelled droplets. Flow fields are presented from applying this methodology over multiple sneezes which reveal that less than 1% of droplets expelled travel at velocities greater than 10 m/s and almost 80% of droplets travel at velocities less than 5 m/s. Furthermore, we observe that some droplets are generated by ligament breakup outside the mouth and some are generated within the respiratory tract. GRAPHIC ABSTRACT: [Image: see text] Springer Berlin Heidelberg 2020-07-18 2020 /pmc/articles/PMC7368616/ /pubmed/32834458 http://dx.doi.org/10.1007/s00348-020-03008-3 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Research Article Bahl, Prateek de Silva, Charitha M. Chughtai, Abrar Ahmad MacIntyre, C. Raina Doolan, Con An experimental framework to capture the flow dynamics of droplets expelled by a sneeze |
title | An experimental framework to capture the flow dynamics of droplets expelled by a sneeze |
title_full | An experimental framework to capture the flow dynamics of droplets expelled by a sneeze |
title_fullStr | An experimental framework to capture the flow dynamics of droplets expelled by a sneeze |
title_full_unstemmed | An experimental framework to capture the flow dynamics of droplets expelled by a sneeze |
title_short | An experimental framework to capture the flow dynamics of droplets expelled by a sneeze |
title_sort | experimental framework to capture the flow dynamics of droplets expelled by a sneeze |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368616/ https://www.ncbi.nlm.nih.gov/pubmed/32834458 http://dx.doi.org/10.1007/s00348-020-03008-3 |
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