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An experimental framework to capture the flow dynamics of droplets expelled by a sneeze

ABSTRACT: Respiratory activities such as sneezing generate pathogen laden droplets that can deposit in the respiratory tract of a susceptible host to initiate infection. The extent of spread of these droplets determines the safe distance between a patient and health care worker. Here, we have presen...

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Autores principales: Bahl, Prateek, de Silva, Charitha M., Chughtai, Abrar Ahmad, MacIntyre, C. Raina, Doolan, Con
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368616/
https://www.ncbi.nlm.nih.gov/pubmed/32834458
http://dx.doi.org/10.1007/s00348-020-03008-3
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author Bahl, Prateek
de Silva, Charitha M.
Chughtai, Abrar Ahmad
MacIntyre, C. Raina
Doolan, Con
author_facet Bahl, Prateek
de Silva, Charitha M.
Chughtai, Abrar Ahmad
MacIntyre, C. Raina
Doolan, Con
author_sort Bahl, Prateek
collection PubMed
description ABSTRACT: Respiratory activities such as sneezing generate pathogen laden droplets that can deposit in the respiratory tract of a susceptible host to initiate infection. The extent of spread of these droplets determines the safe distance between a patient and health care worker. Here, we have presented a method to visualize the droplets expelled by a sneeze using light-sheet illumination. This method of visualization provides images that clearly resolve the velocities of droplets with minimal overlapping trajectories, towards understanding their flow dynamics. Furthermore, we present the image processing techniques required to perform accurate Particle Tracking Velocimetry to understand the motion of expelled droplets. Flow fields are presented from applying this methodology over multiple sneezes which reveal that less than 1% of droplets expelled travel at velocities greater than 10 m/s and almost 80% of droplets travel at velocities less than 5 m/s. Furthermore, we observe that some droplets are generated by ligament breakup outside the mouth and some are generated within the respiratory tract. GRAPHIC ABSTRACT: [Image: see text]
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spelling pubmed-73686162020-07-20 An experimental framework to capture the flow dynamics of droplets expelled by a sneeze Bahl, Prateek de Silva, Charitha M. Chughtai, Abrar Ahmad MacIntyre, C. Raina Doolan, Con Exp Fluids Research Article ABSTRACT: Respiratory activities such as sneezing generate pathogen laden droplets that can deposit in the respiratory tract of a susceptible host to initiate infection. The extent of spread of these droplets determines the safe distance between a patient and health care worker. Here, we have presented a method to visualize the droplets expelled by a sneeze using light-sheet illumination. This method of visualization provides images that clearly resolve the velocities of droplets with minimal overlapping trajectories, towards understanding their flow dynamics. Furthermore, we present the image processing techniques required to perform accurate Particle Tracking Velocimetry to understand the motion of expelled droplets. Flow fields are presented from applying this methodology over multiple sneezes which reveal that less than 1% of droplets expelled travel at velocities greater than 10 m/s and almost 80% of droplets travel at velocities less than 5 m/s. Furthermore, we observe that some droplets are generated by ligament breakup outside the mouth and some are generated within the respiratory tract. GRAPHIC ABSTRACT: [Image: see text] Springer Berlin Heidelberg 2020-07-18 2020 /pmc/articles/PMC7368616/ /pubmed/32834458 http://dx.doi.org/10.1007/s00348-020-03008-3 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Article
Bahl, Prateek
de Silva, Charitha M.
Chughtai, Abrar Ahmad
MacIntyre, C. Raina
Doolan, Con
An experimental framework to capture the flow dynamics of droplets expelled by a sneeze
title An experimental framework to capture the flow dynamics of droplets expelled by a sneeze
title_full An experimental framework to capture the flow dynamics of droplets expelled by a sneeze
title_fullStr An experimental framework to capture the flow dynamics of droplets expelled by a sneeze
title_full_unstemmed An experimental framework to capture the flow dynamics of droplets expelled by a sneeze
title_short An experimental framework to capture the flow dynamics of droplets expelled by a sneeze
title_sort experimental framework to capture the flow dynamics of droplets expelled by a sneeze
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368616/
https://www.ncbi.nlm.nih.gov/pubmed/32834458
http://dx.doi.org/10.1007/s00348-020-03008-3
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