The application of histone deacetylases inhibitors in glioblastoma

The epigenetic abnormality is generally accepted as the key to cancer initiation. Epigenetics that ensure the somatic inheritance of differentiated state is defined as a crucial factor influencing malignant phenotype without altering genotype. Histone modification is one such alteration playing an e...

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Detalles Bibliográficos
Autores principales: Chen, Rui, Zhang, Mengxian, Zhou, Yangmei, Guo, Wenjing, Yi, Ming, Zhang, Ziyan, Ding, Yanpeng, Wang, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368699/
https://www.ncbi.nlm.nih.gov/pubmed/32682428
http://dx.doi.org/10.1186/s13046-020-01643-6

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