Cargando…

Treatment patterns and health outcomes in metastatic renal cell carcinoma patients treated with targeted systemic therapies in the UK

BACKGROUND: Patients with metastatic renal cell carcinoma (mRCC) treated with targeted systemic therapies have demonstrated favourable outcomes in randomised controlled trials, however real-world evidence is limited. Thus, this study aimed to determine the effectiveness of targeted systemic therapie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hawkins, Robert, Fife, Kate, Hurst, Michael, Wang, Meng, Naicker, Niroshini, Nolasco, Sarah, Eisen, Tim, Matakidou, Athena, Gordon, Jason
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368711/ https://www.ncbi.nlm.nih.gov/pubmed/32680483 http://dx.doi.org/10.1186/s12885-020-07154-z

Ejemplares similares

Dose escalation of axitinib on disease progression as a strategy in the treatment of metastatic renal cell carcinoma
por: Doherty, Gary Joseph, et al.
Publicado: (2018)

Identification of low penetrance alleles for lung cancer: The GEnetic Lung CAncer Predisposition Study (GELCAPS)
por: Eisen, Tim, et al.
Publicado: (2008)

Chromosome 15q25 (CHRNA3-CHRNA5) Variation Impacts Indirectly on Lung Cancer Risk
por: Wang, Yufei, et al.
Publicado: (2011)

A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules
por: Espana-Agusti, Judit, et al.
Publicado: (2015)

Systematic review of the relationship between family history and lung cancer risk
por: Matakidou, A, et al.
Publicado: (2005)

Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis
por: Espana-Agusti, Judit, et al.
Publicado: (2017)

Real-world treatment sequencing and survival in previously treated advanced renal cell carcinoma patients receiving nivolumab monotherapy: a UK retrospective cohort study
por: Waddell, T., et al.
Publicado: (2022)

The WIRE study a phase II, multi-arm, multi-centre, non-randomised window-of-opportunity clinical trial platform using a Bayesian adaptive design for proof-of-mechanism of novel treatment strategies in operable renal cell cancer – a study protocol
por: Ursprung, Stephan, et al.
Publicado: (2021)

Case Report: Clinical Experience With Avelumab in Patients With Metastatic Merkel Cell Carcinoma and Brain Metastases Treated in Europe
por: Fife, Kate, et al.
Publicado: (2021)

Impact of COVID-19 pandemic on treatment patterns in metastatic clear cell renal cell carcinoma
por: Aeppli, Stefanie, et al.
Publicado: (2020)

Sunitinib for Metastatic Renal Cell Carcinoma: A Systematic Review and Meta-Analysis of Real-World and Clinical Trials Data
por: Moran, Michael, et al.
Publicado: (2019)

The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload
por: Mohammad, Goran, et al.
Publicado: (2021)

Prospective study evaluating the relative sensitivity of (18)F-NaF PET/CT for detecting skeletal metastases from renal cell carcinoma in comparison to multidetector CT and (99m)Tc-MDP bone scintigraphy, using an adaptive trial design
por: Gerety, E. L., et al.
Publicado: (2015)

The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort
por: Klatte, Tobias, et al.
Publicado: (2019)

Treatment patterns and clinical outcomes in patients with renal cell carcinoma in the UK: insights from the RECCORD registry
por: Wagstaff, J., et al.
Publicado: (2016)

Generation and Characterisation of a Pax8-CreER(T2) Transgenic Line and a Slc22a6-CreER(T2) Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells
por: Espana-Agusti, Judit, et al.
Publicado: (2016)

Patterns, predictors and subsequent outcomes of disease progression in metastatic renal cell carcinoma patients treated with nivolumab
por: Zahoor, Haris, et al.
Publicado: (2018)

Medical treatment of renal cancer: new horizons
por: Greef, Basma, et al.
Publicado: (2016)

Renal cell carcinoma and the use of sorafenib
por: Larkin, James MG, et al.
Publicado: (2006)

The Predicted Impact of Ipilimumab Usage on Survival in Previously Treated Advanced or Metastatic Melanoma in the UK
por: Larkin, James, et al.
Publicado: (2015)

Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis
por: Matakidou, A, et al.
Publicado: (2007)

Prognostic significance of folate metabolism polymorphisms for lung cancer
por: Matakidou, A, et al.
Publicado: (2007)

Improved renal allograft survival for pre-emptive paediatric renal transplant recipients in the UK
por: Marlais, Matko, et al.
Publicado: (2021)

Sunitinib in Metastatic Renal Cell Carcinoma: A Systematic Review of UK Real World Data
por: Argyropulo-Palmer, Miriam, et al.
Publicado: (2015)

Metastatic atypical renal tumour with metanephric characteristics treated with Sunitinib
por: Mohammad, H., et al.
Publicado: (2021)

Assessment of Treatment Patterns for Metastatic Renal Cell Carcinoma in Brazil
por: Bergerot, Paulo G., et al.
Publicado: (2017)

Temporal patterns of wildlife roadkill in the UK
por: Raymond, Sarah, et al.
Publicado: (2021)

Adjuvant Therapy in Renal Cell Carcinoma—Past, Present, and Future()
por: Janowitz, Tobias, et al.
Publicado: (2013)

Phase II clinical trial of capecitabine and gemcitabine chemotherapy in patients with metastatic renal carcinoma
por: Waters, J S, et al.
Publicado: (2004)

CT patterns of organizing pneumonia in patients treated with VEGF/mTOR inhibitors for metastatic renal cell cancer: an observational study
por: Dettmer, Sabine, et al.
Publicado: (2017)

The role of netrin-1 in metastatic renal cell carcinoma treated with sunitinib
por: Frees, Sebastian, et al.
Publicado: (2018)

One year survivor of metastatic renal cell carcinoma treated with pazopanib
por: Inn, Fam Xeng, et al.
Publicado: (2017)

The efficacy and safety of irinotecan cisplatin and mitomycin chemotherapy in sunitinib pre-treated metastatic clear cell renal cancer
por: Powles, Thomas, et al.
Publicado: (2008)

Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib
por: Billemont, B, et al.
Publicado: (2008)

A case of metastatic renal cell carcinoma treated effectively by gemcitabine and sunitinib
por: Morizane, Shuichi, et al.
Publicado: (2012)

Survival in Metastatic Renal Cell Carcinoma Patients Treated With Sunitinib With or Without Cryoablation
por: Gu, Cheng-Yuan, et al.
Publicado: (2021)

Metformin Use and the Outcome of Metastatic Renal Cell Carcinoma Treated with Sunitinib or Pazopanib
por: Fiala, Ondřej, et al.
Publicado: (2021)

Measuring patients’ experience with renal services in the UK: development and validation of the Kidney PREM
por: Hawkins, Janine, et al.
Publicado: (2022)

Markers of inflammation are associated with clinical outcomes in patients with metastatic renal cell carcinoma treated with nivolumab
por: Sznol, Mario, et al.
Publicado: (2015)

Naptumomab Estafenatox: Targeted Immunotherapy with a Novel Immunotoxin
por: Eisen, Tim, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_78vfd8epabh8ma1govbce8kdrj