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Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes

BACKGROUND: We previously identified two acute kidney injury (AKI) sub-phenotypes (AKI-SP1 and AKI-SP2) with different risk of poor clinical outcomes and response to vasopressor therapy. Plasma biomarkers of endothelial dysfunction (tumor necrosis factor receptor-1, angiopoietin-1 and 2) differentia...

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Detalles Bibliográficos
Autores principales: Bhatraju, Pavan K., Cohen, Max, Nagao, Ryan J., Morrell, Eric D., Kosamo, Susanna, Chai, Xin-Ya, Nance, Robin, Dmyterko, Victoria, Delaney, Joseph, Christie, Jason D., Liu, Kathleen D., Mikacenic, Carmen, Gharib, Sina A., Liles, W. Conrad, Zheng, Ying, Christiani, David C., Himmelfarb, Jonathan, Wurfel, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368773/
https://www.ncbi.nlm.nih.gov/pubmed/32680471
http://dx.doi.org/10.1186/s12882-020-01935-1