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Slc6a3-dependent expression of a CAPS-associated Nlrp3 allele results in progressive behavioral abnormalities and neuroinflammation in aging mice

BACKGROUND: An association between neuroinflammation and age-related neurologic disorders has been established but the molecular mechanisms and cell types involved have not been thoroughly characterized. Activity of the proinflammatory NLRP3 inflammasome is implicated in Alzheimer’s and Parkinson’s...

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Detalles Bibliográficos
Autores principales:	von Herrmann, Katharine M., Anderson, Faith L., Martinez, Eileen M., Young, Alison L., Havrda, Matthew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368774/ https://www.ncbi.nlm.nih.gov/pubmed/32680528 http://dx.doi.org/10.1186/s12974-020-01866-6

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