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MBNL1 reverses the proliferation defect of skeletal muscle satellite cells in myotonic dystrophy type 1 by inhibiting autophagy via the mTOR pathway

Skeletal muscle atrophy is one of the clinical symptoms of myotonic dystrophy type 1 (DM1). A decline in skeletal muscle regeneration is an important contributor to muscle atrophy. Skeletal muscle satellite cells (SSCs) drive skeletal muscle regeneration. Increased autophagy can reduce the prolifera...

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Detalles Bibliográficos
Autores principales:	Song, Kai-Yi, Guo, Xiu-Ming, Wang, Hui-Qi, Zhang, Lei, Huang, Si-Yuan, Huo, Ying-Chao, Zhang, Gang, Feng, Jin-Zhou, Zhang, Rong-Rong, Ma, Yue, Hu, Qing-Zhe, Qin, Xin-Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368861/ https://www.ncbi.nlm.nih.gov/pubmed/32683410 http://dx.doi.org/10.1038/s41419-020-02756-8

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