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Penalized logistic regression based on [Formula: see text] penalty for high-dimensional DNA methylation data

BACKGROUND: DNA methylation is a molecular modification of DNA that is vital and occurs in gene expression. In cancer tissues, the 5’–C–phosphate–G–3’(CpG) rich regions are abnormally hypermethylated or hypomethylated. Therefore, it is useful to find out the diseased CpG sites by employing specific...

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Detalles Bibliográficos
Autores principales: Jiang, Hong-Kun, Liang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369078/
https://www.ncbi.nlm.nih.gov/pubmed/32364148
http://dx.doi.org/10.3233/THC-209016