Low-depth whole genome sequencing reveals copy number variations associated with higher pathologic grading and more aggressive subtypes of lung non-mucinous adenocarcinoma

OBJECTIVE: Histology grade, subtypes and TNM stage of lung adenocarcinomas are useful predictors of prognosis and survival. The aim of the study was to investigate the relationship between chromosomal instability, morphological subtypes and the grading system used in lung non-mucinous adenocarcinoma...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Zhang, Lin, He, Lei, Cui, Di, Liu, Chenglong, Yin, Liangyu, Zhang, Min, Jiang, Lei, Gong, Yuyan, Wu, Wang, Liu, Bi, Li, Xiaoyu, Cram, David S, Liu, Dongge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369181/
https://www.ncbi.nlm.nih.gov/pubmed/32694898
http://dx.doi.org/10.21147/j.issn.1000-9604.2020.03.05

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