miR-188-5p Promotes Tumor Growth by Targeting CD2AP Through PI3K/AKT/mTOR Signaling in Children with Acute Promyelocytic Leukemia

PURPOSE: Pediatric acute promyelocytic leukemia (APL) accounts for 10% of pediatric acute myelogenous leukemia (AML) case and is accompanied by a tendency to hemorrhage. miR-188-5p plays an important role in adult AML. Therefore, the purpose of this study was to explore the effects of miR-188-5p on...

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Detalles Bibliográficos
Autores principales: Wang, Dao, Chen, Jiao, Ding, Yanjie, Kong, Huimin, You, Hongliang, Zhao, Yanting, Wei, Huixia, Liu, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369302/
https://www.ncbi.nlm.nih.gov/pubmed/32764959
http://dx.doi.org/10.2147/OTT.S244813

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