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Rpt2 proteasome subunit reduction causes Parkinson's disease like symptoms in Drosophila
The dysfunction of the proteasome-ubiquitin system is commonly reported in several neurodegenerative diseases. Post mortem samples of brains of patients with Parkinson´s disease present cytoplasmic inclusions that are rich in proteins such as ubiquitin, Tau, and α-synuclein. In Parkinson´s disease,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369354/ https://www.ncbi.nlm.nih.gov/pubmed/32715147 http://dx.doi.org/10.1016/j.ibror.2020.07.001 |