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Rpt2 proteasome subunit reduction causes Parkinson's disease like symptoms in Drosophila

The dysfunction of the proteasome-ubiquitin system is commonly reported in several neurodegenerative diseases. Post mortem samples of brains of patients with Parkinson´s disease present cytoplasmic inclusions that are rich in proteins such as ubiquitin, Tau, and α-synuclein. In Parkinson´s disease,...

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Detalles Bibliográficos
Autores principales: Fernández-Cruz, Iván, Sánchez-Díaz, Iván, Narváez-Padilla, Verónica, Reynaud, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369354/
https://www.ncbi.nlm.nih.gov/pubmed/32715147
http://dx.doi.org/10.1016/j.ibror.2020.07.001

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