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Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases

To better understand the dynamics of zoonotic diseases, we propose a deterministic mathematical model to study the dynamics of zoonotic brucellosis with a focus on developing countries. The model contains all the relevant biological details, including indirect transmission by the environment. We ana...

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Autor principal: Mhlanga, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369659/
https://www.ncbi.nlm.nih.gov/pubmed/32733595
http://dx.doi.org/10.1155/2020/6584323
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author Mhlanga, A.
author_facet Mhlanga, A.
author_sort Mhlanga, A.
collection PubMed
description To better understand the dynamics of zoonotic diseases, we propose a deterministic mathematical model to study the dynamics of zoonotic brucellosis with a focus on developing countries. The model contains all the relevant biological details, including indirect transmission by the environment. We analyze the essential dynamic behavior of the model and perform an optimal control study to design effective prevention and intervention strategies. The sensitivity analysis of the model parameters is performed. The aim of the controls is tied to reducing the number of infected humans, through health promotional programs within the affected communities. The Pontryagin's Maximum Principle is used to characterize the optimal level of the controls, and the resulting optimality system is solved numerically. Overall, the study demonstrates that through health promotional programs on zoonotic diseases among villagers, it is vital that they should be conducted with high efficacy.
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spelling pubmed-73696592020-07-29 Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases Mhlanga, A. Comput Math Methods Med Research Article To better understand the dynamics of zoonotic diseases, we propose a deterministic mathematical model to study the dynamics of zoonotic brucellosis with a focus on developing countries. The model contains all the relevant biological details, including indirect transmission by the environment. We analyze the essential dynamic behavior of the model and perform an optimal control study to design effective prevention and intervention strategies. The sensitivity analysis of the model parameters is performed. The aim of the controls is tied to reducing the number of infected humans, through health promotional programs within the affected communities. The Pontryagin's Maximum Principle is used to characterize the optimal level of the controls, and the resulting optimality system is solved numerically. Overall, the study demonstrates that through health promotional programs on zoonotic diseases among villagers, it is vital that they should be conducted with high efficacy. Hindawi 2020-07-11 /pmc/articles/PMC7369659/ /pubmed/32733595 http://dx.doi.org/10.1155/2020/6584323 Text en Copyright © 2020 A. Mhlanga. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mhlanga, A.
Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases
title Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases
title_full Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases
title_fullStr Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases
title_full_unstemmed Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases
title_short Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases
title_sort assessing the impact of optimal health education programs on the control of zoonotic diseases
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369659/
https://www.ncbi.nlm.nih.gov/pubmed/32733595
http://dx.doi.org/10.1155/2020/6584323
work_keys_str_mv AT mhlangaa assessingtheimpactofoptimalhealtheducationprogramsonthecontrolofzoonoticdiseases