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Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases
To better understand the dynamics of zoonotic diseases, we propose a deterministic mathematical model to study the dynamics of zoonotic brucellosis with a focus on developing countries. The model contains all the relevant biological details, including indirect transmission by the environment. We ana...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369659/ https://www.ncbi.nlm.nih.gov/pubmed/32733595 http://dx.doi.org/10.1155/2020/6584323 |
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author | Mhlanga, A. |
author_facet | Mhlanga, A. |
author_sort | Mhlanga, A. |
collection | PubMed |
description | To better understand the dynamics of zoonotic diseases, we propose a deterministic mathematical model to study the dynamics of zoonotic brucellosis with a focus on developing countries. The model contains all the relevant biological details, including indirect transmission by the environment. We analyze the essential dynamic behavior of the model and perform an optimal control study to design effective prevention and intervention strategies. The sensitivity analysis of the model parameters is performed. The aim of the controls is tied to reducing the number of infected humans, through health promotional programs within the affected communities. The Pontryagin's Maximum Principle is used to characterize the optimal level of the controls, and the resulting optimality system is solved numerically. Overall, the study demonstrates that through health promotional programs on zoonotic diseases among villagers, it is vital that they should be conducted with high efficacy. |
format | Online Article Text |
id | pubmed-7369659 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-73696592020-07-29 Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases Mhlanga, A. Comput Math Methods Med Research Article To better understand the dynamics of zoonotic diseases, we propose a deterministic mathematical model to study the dynamics of zoonotic brucellosis with a focus on developing countries. The model contains all the relevant biological details, including indirect transmission by the environment. We analyze the essential dynamic behavior of the model and perform an optimal control study to design effective prevention and intervention strategies. The sensitivity analysis of the model parameters is performed. The aim of the controls is tied to reducing the number of infected humans, through health promotional programs within the affected communities. The Pontryagin's Maximum Principle is used to characterize the optimal level of the controls, and the resulting optimality system is solved numerically. Overall, the study demonstrates that through health promotional programs on zoonotic diseases among villagers, it is vital that they should be conducted with high efficacy. Hindawi 2020-07-11 /pmc/articles/PMC7369659/ /pubmed/32733595 http://dx.doi.org/10.1155/2020/6584323 Text en Copyright © 2020 A. Mhlanga. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Mhlanga, A. Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases |
title | Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases |
title_full | Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases |
title_fullStr | Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases |
title_full_unstemmed | Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases |
title_short | Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases |
title_sort | assessing the impact of optimal health education programs on the control of zoonotic diseases |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369659/ https://www.ncbi.nlm.nih.gov/pubmed/32733595 http://dx.doi.org/10.1155/2020/6584323 |
work_keys_str_mv | AT mhlangaa assessingtheimpactofoptimalhealtheducationprogramsonthecontrolofzoonoticdiseases |