Pristimerin Exacerbates Cellular Injury in Conditionally Reprogrammed Patient-Derived Lung Adenocarcinoma Cells by Aggravating Mitochondrial Impairment and Endoplasmic Reticulum Stress through EphB4/CDC42/N-WASP Signaling

Lung cancer is the most common and lethal malignant disease for which the development of efficacious chemotherapeutic agents remains an urgent need. Pristimerin (PRIS), a natural bioactive component isolated from various plant species in the Celastraceae and Hippocrateaceae families, has been report...

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Detalles Bibliográficos
Autores principales: Tang, Yubo, Lei, Yiyan, Huang, Shuai, Li, Zhangyan, Chen, Xiangtian, Luo, Honghe, Cheng, Chao, Chen, Jie, Zou, Xuenong, Chen, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369684/
https://www.ncbi.nlm.nih.gov/pubmed/32733636
http://dx.doi.org/10.1155/2020/7409853

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