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Extracellular Matrix Stiffness and Composition Regulate the Myofibroblast Differentiation of Vaginal Fibroblasts
Fibroblast to myofibroblast differentiation is a key feature of wound-healing in soft tissues, including the vagina. Vaginal fibroblasts maintain the integrity of the vaginal wall tissues, essential to keep pelvic organs in place and avoid pelvic organ prolapse (POP). The micro-environment of vagina...
Autores principales: | Ruiz-Zapata, Alejandra M., Heinz, Andrea, Kerkhof, Manon H., van de Westerlo-van Rijt, Cindy, Schmelzer, Christian E. H., Stoop, Reinout, Kluivers, Kirsten B., Oosterwijk, Egbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369731/ https://www.ncbi.nlm.nih.gov/pubmed/32635512 http://dx.doi.org/10.3390/ijms21134762 |
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