Sequesterpene Lactones Isolated from a Brazilian Cerrado Plant (Eremanthus spp.) as Anti-Proliferative Compounds, Characterized by Functional and Proteomic Analysis, Are Candidates for New Therapeutics in Glioblastoma

Gliomas are responsible for more than 60% of all primary brain tumors. Glioblastoma multiforme (GBM), a grade IV tumor (WHO), is one of the most frequent and malignant gliomas. Despite two decades of advances in the discovery of new markers for GBM, the chemotherapy of choice falls to temozolomide a...

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Detalles Bibliográficos
Autores principales: Izumi, Clarice, Laure, Helen Julie, Barbosa, Nayara Gonçalves, Hassibe Thomé, Carolina, Aguiar Ferreira, Germano, Paulo Barreto Sousa, João, Peporine Lopes, Norberto, César Rosa, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369765/
https://www.ncbi.nlm.nih.gov/pubmed/32630308
http://dx.doi.org/10.3390/ijms21134713

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