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The Fungal Iron Chelator Desferricoprogen Inhibits Atherosclerotic Plaque Formation

Hemoglobin, heme and iron are implicated in the progression of atherosclerosis. Therefore, we investigated whether the hydrophobic fungal iron chelator siderophore, desferricoprogen (DFC) inhibits atherosclerosis. DFC reduced atherosclerotic plaque formation in ApoE(−/−) mice on an atherogenic diet....

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Detalles Bibliográficos
Autores principales:	Potor, László, Sikura, Katalin Éva, Hegedűs, Hajnalka, Pethő, Dávid, Szabó, Zsuzsa, Szigeti, Zsuzsa M, Pócsi, István, Trencsényi, György, Szikra, Dezső, Garai, Ildikó, Gáll, Tamás, Combi, Zsolt, Kappelmayer, János, Balla, György, Balla, József
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369830/ https://www.ncbi.nlm.nih.gov/pubmed/32635347 http://dx.doi.org/10.3390/ijms21134746

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