Genetic Variants in the FGB and FGG Genes Mapping in the Beta and Gamma Nodules of the Fibrinogen Molecule in Congenital Quantitative Fibrinogen Disorders Associated with a Thrombotic Phenotype

Fibrinogen is a hexameric plasmatic glycoprotein composed of pairs of three chains (Aα, Bβ, and γ), which play an essential role in hemostasis. Conversion of fibrinogen to insoluble polymer fibrin gives structural stability, strength, and adhesive surfaces for growing blood clots. Equally important,...

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Detalles Bibliográficos
Autores principales: Simurda, Tomas, Brunclikova, Monika, Asselta, Rosanna, Caccia, Sonia, Zolkova, Jana, Kolkova, Zuzana, Loderer, Dusan, Skornova, Ingrid, Hudecek, Jan, Lasabova, Zora, Stasko, Jan, Kubisz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369898/
https://www.ncbi.nlm.nih.gov/pubmed/32610551
http://dx.doi.org/10.3390/ijms21134616

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