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Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery

Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions,...

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Detalles Bibliográficos
Autores principales: Municoy, Sofia, Álvarez Echazú, María I., Antezana, Pablo E., Galdopórpora, Juan M., Olivetti, Christian, Mebert, Andrea M., Foglia, María L., Tuttolomondo, María V., Alvarez, Gisela S., Hardy, John G., Desimone, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369929/
https://www.ncbi.nlm.nih.gov/pubmed/32630690
http://dx.doi.org/10.3390/ijms21134724
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author Municoy, Sofia
Álvarez Echazú, María I.
Antezana, Pablo E.
Galdopórpora, Juan M.
Olivetti, Christian
Mebert, Andrea M.
Foglia, María L.
Tuttolomondo, María V.
Alvarez, Gisela S.
Hardy, John G.
Desimone, Martin F.
author_facet Municoy, Sofia
Álvarez Echazú, María I.
Antezana, Pablo E.
Galdopórpora, Juan M.
Olivetti, Christian
Mebert, Andrea M.
Foglia, María L.
Tuttolomondo, María V.
Alvarez, Gisela S.
Hardy, John G.
Desimone, Martin F.
author_sort Municoy, Sofia
collection PubMed
description Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions, structure, and/or dimensions. The specificity of stimuli response, and ability to respond to endogenous cues inherently present in living systems provide possibilities to develop novel tissue engineering and drug delivery strategies (for example materials composed of stimuli responsive polymers that self-assemble or undergo phase transitions or morphology transformations). Herein, smart materials as controlled drug release vehicles for tissue engineering are described, highlighting their potential for the delivery of precise quantities of drugs at specific locations and times promoting the controlled repair or remodeling of tissues.
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spelling pubmed-73699292020-07-21 Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery Municoy, Sofia Álvarez Echazú, María I. Antezana, Pablo E. Galdopórpora, Juan M. Olivetti, Christian Mebert, Andrea M. Foglia, María L. Tuttolomondo, María V. Alvarez, Gisela S. Hardy, John G. Desimone, Martin F. Int J Mol Sci Review Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions, structure, and/or dimensions. The specificity of stimuli response, and ability to respond to endogenous cues inherently present in living systems provide possibilities to develop novel tissue engineering and drug delivery strategies (for example materials composed of stimuli responsive polymers that self-assemble or undergo phase transitions or morphology transformations). Herein, smart materials as controlled drug release vehicles for tissue engineering are described, highlighting their potential for the delivery of precise quantities of drugs at specific locations and times promoting the controlled repair or remodeling of tissues. MDPI 2020-07-02 /pmc/articles/PMC7369929/ /pubmed/32630690 http://dx.doi.org/10.3390/ijms21134724 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Municoy, Sofia
Álvarez Echazú, María I.
Antezana, Pablo E.
Galdopórpora, Juan M.
Olivetti, Christian
Mebert, Andrea M.
Foglia, María L.
Tuttolomondo, María V.
Alvarez, Gisela S.
Hardy, John G.
Desimone, Martin F.
Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery
title Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery
title_full Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery
title_fullStr Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery
title_full_unstemmed Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery
title_short Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery
title_sort stimuli-responsive materials for tissue engineering and drug delivery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369929/
https://www.ncbi.nlm.nih.gov/pubmed/32630690
http://dx.doi.org/10.3390/ijms21134724
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