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Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery
Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions,...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369929/ https://www.ncbi.nlm.nih.gov/pubmed/32630690 http://dx.doi.org/10.3390/ijms21134724 |
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author | Municoy, Sofia Álvarez Echazú, María I. Antezana, Pablo E. Galdopórpora, Juan M. Olivetti, Christian Mebert, Andrea M. Foglia, María L. Tuttolomondo, María V. Alvarez, Gisela S. Hardy, John G. Desimone, Martin F. |
author_facet | Municoy, Sofia Álvarez Echazú, María I. Antezana, Pablo E. Galdopórpora, Juan M. Olivetti, Christian Mebert, Andrea M. Foglia, María L. Tuttolomondo, María V. Alvarez, Gisela S. Hardy, John G. Desimone, Martin F. |
author_sort | Municoy, Sofia |
collection | PubMed |
description | Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions, structure, and/or dimensions. The specificity of stimuli response, and ability to respond to endogenous cues inherently present in living systems provide possibilities to develop novel tissue engineering and drug delivery strategies (for example materials composed of stimuli responsive polymers that self-assemble or undergo phase transitions or morphology transformations). Herein, smart materials as controlled drug release vehicles for tissue engineering are described, highlighting their potential for the delivery of precise quantities of drugs at specific locations and times promoting the controlled repair or remodeling of tissues. |
format | Online Article Text |
id | pubmed-7369929 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73699292020-07-21 Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery Municoy, Sofia Álvarez Echazú, María I. Antezana, Pablo E. Galdopórpora, Juan M. Olivetti, Christian Mebert, Andrea M. Foglia, María L. Tuttolomondo, María V. Alvarez, Gisela S. Hardy, John G. Desimone, Martin F. Int J Mol Sci Review Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions, structure, and/or dimensions. The specificity of stimuli response, and ability to respond to endogenous cues inherently present in living systems provide possibilities to develop novel tissue engineering and drug delivery strategies (for example materials composed of stimuli responsive polymers that self-assemble or undergo phase transitions or morphology transformations). Herein, smart materials as controlled drug release vehicles for tissue engineering are described, highlighting their potential for the delivery of precise quantities of drugs at specific locations and times promoting the controlled repair or remodeling of tissues. MDPI 2020-07-02 /pmc/articles/PMC7369929/ /pubmed/32630690 http://dx.doi.org/10.3390/ijms21134724 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Municoy, Sofia Álvarez Echazú, María I. Antezana, Pablo E. Galdopórpora, Juan M. Olivetti, Christian Mebert, Andrea M. Foglia, María L. Tuttolomondo, María V. Alvarez, Gisela S. Hardy, John G. Desimone, Martin F. Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery |
title | Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery |
title_full | Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery |
title_fullStr | Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery |
title_full_unstemmed | Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery |
title_short | Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery |
title_sort | stimuli-responsive materials for tissue engineering and drug delivery |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369929/ https://www.ncbi.nlm.nih.gov/pubmed/32630690 http://dx.doi.org/10.3390/ijms21134724 |
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