The Differential Effect of Carbon Dots on Gene Expression and DNA Methylation of Human Embryonic Lung Fibroblasts as a Function of Surface Charge and Dose

This study presents a toxicological evaluation of two types of carbon dots (CD), similar in size (<10 nm) but differing in surface charge. Whole-genome mRNA and miRNA expression (RNAseq), as well as gene-specific DNA methylation changes, were analyzed in human embryonic lung fibroblasts (HEL 1246...

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Detalles Bibliográficos
Autores principales: Sima, Michal, Vrbova, Kristyna, Zavodna, Tana, Honkova, Katerina, Chvojkova, Irena, Ambroz, Antonin, Klema, Jiri, Rossnerova, Andrea, Polakova, Katerina, Malina, Tomas, Belza, Jan, Topinka, Jan, Rossner, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369946/
https://www.ncbi.nlm.nih.gov/pubmed/32635498
http://dx.doi.org/10.3390/ijms21134763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369946/
https://www.ncbi.nlm.nih.gov/pubmed/32635498
http://dx.doi.org/10.3390/ijms21134763

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