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Rounding up the Usual Suspects: Assessing Yorkie, AP-1, and Stat Coactivation in Tumorigenesis

Can hyperactivation of a few key signaling effectors be the underlying reason for the majority of epithelial cancers despite different driver mutations? Here, to address this question, we use the Drosophila model, which allows analysis of gene expression from tumors with known initiating mutations....

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Detalles Bibliográficos
Autores principales: Hamaratoglu, Fisun, Atkins, Mardelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370090/
https://www.ncbi.nlm.nih.gov/pubmed/32605129
http://dx.doi.org/10.3390/ijms21134580

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