Cargando…
Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity
Obesity is a characteristic of COVID-19 patients and the risk of malnutrition can be underestimated due to excess of fat: a paradoxical danger. Long ICU hospitalization exposes patients to a high risk of wasting and loss of lean body mass. The complex management precludes the detection of anthropome...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370146/ https://www.ncbi.nlm.nih.gov/pubmed/32630032 http://dx.doi.org/10.3390/ijms21134670 |
_version_ | 1783560931690676224 |
---|---|
author | Gualtieri, Paola Falcone, Carmela Romano, Lorenzo Macheda, Sebastiano Correale, Pierpaolo Arciello, Pietro Polimeni, Nicola De Lorenzo, Antonino |
author_facet | Gualtieri, Paola Falcone, Carmela Romano, Lorenzo Macheda, Sebastiano Correale, Pierpaolo Arciello, Pietro Polimeni, Nicola De Lorenzo, Antonino |
author_sort | Gualtieri, Paola |
collection | PubMed |
description | Obesity is a characteristic of COVID-19 patients and the risk of malnutrition can be underestimated due to excess of fat: a paradoxical danger. Long ICU hospitalization exposes patients to a high risk of wasting and loss of lean body mass. The complex management precludes the detection of anthropometric parameters for the definition and monitoring of the nutritional status. The use of imaging diagnostics for body composition could help to recognize and treat patients at increased risk of wasting with targeted pathways. COVID-19 patients admitted to the ICU underwent computed tomography within 24 h and about 20 days later, to evaluate the parameters of the body and liver composition. The main results were the loss of the lean mass index and a greater increase in liver attenuation in obese subjects. These could be co-caused by COVID-19, prolonged bed rest, the complex medical nutritional therapy, and the starting condition of low-grade inflammation of the obese. The assessment of nutritional status, with body composition applied to imaging diagnostics and metabolic profiles in COVID-19, will assist in prescribing appropriate medical nutritional therapy. This will reduce recovery times and complications caused by frailty. |
format | Online Article Text |
id | pubmed-7370146 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73701462020-07-21 Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity Gualtieri, Paola Falcone, Carmela Romano, Lorenzo Macheda, Sebastiano Correale, Pierpaolo Arciello, Pietro Polimeni, Nicola De Lorenzo, Antonino Int J Mol Sci Article Obesity is a characteristic of COVID-19 patients and the risk of malnutrition can be underestimated due to excess of fat: a paradoxical danger. Long ICU hospitalization exposes patients to a high risk of wasting and loss of lean body mass. The complex management precludes the detection of anthropometric parameters for the definition and monitoring of the nutritional status. The use of imaging diagnostics for body composition could help to recognize and treat patients at increased risk of wasting with targeted pathways. COVID-19 patients admitted to the ICU underwent computed tomography within 24 h and about 20 days later, to evaluate the parameters of the body and liver composition. The main results were the loss of the lean mass index and a greater increase in liver attenuation in obese subjects. These could be co-caused by COVID-19, prolonged bed rest, the complex medical nutritional therapy, and the starting condition of low-grade inflammation of the obese. The assessment of nutritional status, with body composition applied to imaging diagnostics and metabolic profiles in COVID-19, will assist in prescribing appropriate medical nutritional therapy. This will reduce recovery times and complications caused by frailty. MDPI 2020-06-30 /pmc/articles/PMC7370146/ /pubmed/32630032 http://dx.doi.org/10.3390/ijms21134670 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Gualtieri, Paola Falcone, Carmela Romano, Lorenzo Macheda, Sebastiano Correale, Pierpaolo Arciello, Pietro Polimeni, Nicola De Lorenzo, Antonino Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity |
title | Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity |
title_full | Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity |
title_fullStr | Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity |
title_full_unstemmed | Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity |
title_short | Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity |
title_sort | body composition findings by computed tomography in sars-cov-2 patients: increased risk of muscle wasting in obesity |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370146/ https://www.ncbi.nlm.nih.gov/pubmed/32630032 http://dx.doi.org/10.3390/ijms21134670 |
work_keys_str_mv | AT gualtieripaola bodycompositionfindingsbycomputedtomographyinsarscov2patientsincreasedriskofmusclewastinginobesity AT falconecarmela bodycompositionfindingsbycomputedtomographyinsarscov2patientsincreasedriskofmusclewastinginobesity AT romanolorenzo bodycompositionfindingsbycomputedtomographyinsarscov2patientsincreasedriskofmusclewastinginobesity AT machedasebastiano bodycompositionfindingsbycomputedtomographyinsarscov2patientsincreasedriskofmusclewastinginobesity AT correalepierpaolo bodycompositionfindingsbycomputedtomographyinsarscov2patientsincreasedriskofmusclewastinginobesity AT arciellopietro bodycompositionfindingsbycomputedtomographyinsarscov2patientsincreasedriskofmusclewastinginobesity AT polimeninicola bodycompositionfindingsbycomputedtomographyinsarscov2patientsincreasedriskofmusclewastinginobesity AT delorenzoantonino bodycompositionfindingsbycomputedtomographyinsarscov2patientsincreasedriskofmusclewastinginobesity |