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Nicotinamide Phosphoribosyltransferase (Nampt)/Nicotinamide Adenine Dinucleotide (NAD) Axis Suppresses Atrial Fibrillation by Modulating the Calcium Handling Pathway

Aging and obesity are the most prominent risk factors for onset of atrial fibrillation (AF). Nicotinamide phosphoribosyltransferase (Nampt) is the rate-limiting enzyme that catalyzes nicotinamide adenine dinucleotide (NAD) activity. Nampt and NAD are essential for maintenance of cellular redox homeo...

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Detalles Bibliográficos
Autores principales: Feng, Duo, Xu, DongZhu, Murakoshi, Nobuyuki, Tajiri, Kazuko, Qin, Rujie, Yonebayashi, Saori, Okabe, Yuta, Li, Siqi, Yuan, Zixun, Aonuma, Kazutaka, Ieda, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370160/
https://www.ncbi.nlm.nih.gov/pubmed/32629939
http://dx.doi.org/10.3390/ijms21134655