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Signaling Through Purinergic Receptor P2Y(2) Enhances Macrophage IL-1β Production

The release of nucleotides during necrosis or apoptosis has been described to have both proinflammatory and anti-inflammatory effect on the surrounding cells. Here we describe how low concentrations of UTP and ATP applied during macrophage priming enhance IL-1β production when subsequently the NLRP3...

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Detalles Bibliográficos
Autores principales: de la Rosa, Gonzalo, Gómez, Ana I., Baños, María C., Pelegrín, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370188/
https://www.ncbi.nlm.nih.gov/pubmed/32630144
http://dx.doi.org/10.3390/ijms21134686