Cargando…

β-Arrestin 2 and ERK1/2 Are Important Mediators Engaged in Close Cooperation between TRPV1 and µ-Opioid Receptors in the Plasma Membrane

The interactions between TRPV1 and µ-opioid receptors (MOR) have recently attracted much attention because these two receptors play important roles in pain pathways and can apparently modulate each other’s functioning. However, the knowledge about signaling interactions and crosstalk between these t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Melkes, Barbora, Markova, Vendula, Hejnova, Lucie, Novotny, Jiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370190/ https://www.ncbi.nlm.nih.gov/pubmed/32610605 http://dx.doi.org/10.3390/ijms21134626

Ejemplares similares

Opioids Alleviate Oxidative Stress via the Nrf2/HO-1 Pathway in LPS-Stimulated Microglia
por: Shivling Mali, Akash, et al.
Publicado: (2023)

Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist
por: Doi, Seira, et al.
Publicado: (2016)

β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons
por: Rowan, Matthew P, et al.
Publicado: (2014)

Activation of Mu Opioid Receptors Sensitizes Transient Receptor Potential Vanilloid Type 1 (TRPV1) via β-Arrestin-2-Mediated Cross-Talk
por: Rowan, Matthew P., et al.
Publicado: (2014)

Phosphorylation of β-arrestin2 at Thr(383) by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs
por: Cassier, Elisabeth, et al.
Publicado: (2017)

Opioid-Modulated Receptor Localization and Erk1/2 Phosphorylation in Cells Coexpressing μ-Opioid and Nociceptin Receptors
por: Zhuo, Guan-Yu, et al.
Publicado: (2023)

β-arrestin-1 and β-arrestin-2 Restrain MRGPRX2-Triggered Degranulation and ERK1/2 Activation in Human Skin Mast Cells
por: Wang, Zhao, et al.
Publicado: (2022)

Effects of Renal Denervation on the Enhanced Renal Vascular Responsiveness to Angiotensin II in High-Output Heart Failure: Angiotensin II Receptor Binding Assessment and Functional Studies in Ren-2 Transgenic Hypertensive Rats
por: Honetschlägerová, Zuzana, et al.
Publicado: (2021)

The day/night difference in the circadian clock's response to acute lipopolysaccharide and the rhythmic Stat3 expression in the rat suprachiasmatic nucleus
por: Moravcová, Simona, et al.
Publicado: (2018)

Proteomic Analysis Unveils Expressional Changes in Cytoskeleton- and Synaptic Plasticity-Associated Proteins in Rat Brain Six Months after Withdrawal from Morphine
por: Drastichova, Zdenka, et al.
Publicado: (2021)

The Effect of Arrestin Conformation on the Recruitment of c-Raf1, MEK1, and ERK1/2 Activation
por: Coffa, Sergio, et al.
Publicado: (2011)

Alterations in the Proteome and Phosphoproteome Profiles of Rat Hippocampus after Six Months of Morphine Withdrawal: Comparison with the Forebrain Cortex
por: Ujcikova, Hana, et al.
Publicado: (2021)

β-Arrestin2 Is Critically Involved in the Differential Regulation of Phosphosignaling Pathways by Thyrotropin-Releasing Hormone and Taltirelin
por: Drastichova, Zdenka, et al.
Publicado: (2022)

Usefulness for the combination of G protein- and β-arrestin-biased ligands of μ-opioid receptors: Prevention of antinociceptive tolerance
por: Mori, Tomohisa, et al.
Publicado: (2017)

β-Arrestin–Dependent Endocytosis of Proteinase-Activated Receptor 2 Is Required for Intracellular Targeting of Activated Erk1/2
por: DeFea, K.A., et al.
Publicado: (2000)

Agonist dependency of the second phase access of β-arrestin 2 to the heteromeric µ-V1b receptor
por: Ngamlertwong, Nuttawadee, et al.
Publicado: (2021)

SUN-479 Role of β-arrestin2 in ERK 1/2 Activation Mediated by Corticotropin-Releasing Factor Receptor Type 1
por: Parra Mercado, Gabriela, et al.
Publicado: (2019)

Adenylyl Cyclase Signaling in the Developing Chick Heart: The Deranging Effect of Antiarrhythmic Drugs
por: Hejnova, Lucie, et al.
Publicado: (2014)

LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1
por: Rodriguiz, Ramona M., et al.
Publicado: (2021)

TRPV1 Activation Promotes β-arrestin2 Interaction with the Ribosomal Biogenesis Machinery in the Nucleolus: Implications for p53 Regulation and Neurite Outgrowth
por: Hassan, Ahmed, et al.
Publicado: (2021)

ß-arrestin 2 germline knockout does not attenuate opioid respiratory depression
por: Bachmutsky, Iris, et al.
Publicado: (2021)

Effects of the Dopamine D2 Allosteric Modulator, PAOPA, on the Expression of GRK2, Arrestin-3, ERK1/2, and on Receptor Internalization
por: Basu, Dipannita, et al.
Publicado: (2013)

Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK
por: Lin, Jaung-Geng, et al.
Publicado: (2015)

Side Effects of Opioids Are Ameliorated by Regulating TRPV1 Receptors
por: Wang, Xiaqing, et al.
Publicado: (2022)

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells
por: Møller, Thor C., et al.
Publicado: (2020)

Expression profiles of TRPV1, TRPV4, TLR4 and ERK1/2 in the dorsal root ganglionic neurons of a cancer-induced neuropathy rat model
por: Maqboul, Ahmad, et al.
Publicado: (2018)

Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart
por: Gorbunov, Alexandr S., et al.
Publicado: (2019)

Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin
por: Kahsai, Alem W., et al.
Publicado: (2023)

β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4
por: D’Agostino, Gianluca, et al.
Publicado: (2020)

Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice
por: He, Li, et al.
Publicado: (2021)

Silencing of spinal Trpv1 attenuates neuropathic pain in rats by inhibiting CAMKII expression and ERK2 phosphorylation
por: Guo, Shao-Hui, et al.
Publicado: (2019)

Arresting a Transient Receptor Potential (TRP) Channel: β-ARRESTIN 1 MEDIATES UBIQUITINATION AND FUNCTIONAL DOWN-REGULATION OF TRPV4
por: Shukla, Arun K., et al.
Publicado: (2010)

The μ opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway
por: Vetter, Irina, et al.
Publicado: (2006)

Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation
por: Piekielna-Ciesielska, Justyna, et al.
Publicado: (2020)

Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension
por: Willets, Jonathon M., et al.
Publicado: (2015)

Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2
por: Lam, Hoa, et al.
Publicado: (2011)

Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases
por: Liu, Haiping, et al.
Publicado: (2023)

β(2)-Adrenoceptor Activation Stimulates IL-6 Production via PKA, ERK1/2, Src, and Beta-Arrestin2 Signaling Pathways in Human Bronchial Epithelia
por: Zhang, Rui-Gang, et al.
Publicado: (2021)

Antinociceptive Effects of Cardamonin in Mice: Possible Involvement of TRPV(1), Glutamate, and Opioid Receptors
por: Ping, Chung Pui, et al.
Publicado: (2018)

Acupuncture Alleviates Colorectal Hypersensitivity and Correlates with the Regulatory Mechanism of TrpV1 and p-ERK
por: Wang, Shao-Jun, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qnqclt2ar65dnidbmkttim2qbg