Cargando…

Gonadal Hormones E2 and P Mitigate Cerebral Ischemia-Induced Upregulation of the AIM2 and NLRC4 Inflammasomes in Rats

Acute ischemic stroke (AIS) is a devastating neurological condition with a lack of neuroprotective therapeutic options, despite the reperfusion modalities thrombolysis and thrombectomy. Post-ischemic brain damage is aggravated by an excessive inflammatory cascade involving the activation and regulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Habib, Pardes, Harms, Julie, Zendedel, Adib, Beyer, Cordian, Slowik, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370209/ https://www.ncbi.nlm.nih.gov/pubmed/32645874 http://dx.doi.org/10.3390/ijms21134795

Ejemplares similares

Transient Focal Cerebral Ischemia Leads to miRNA Alterations in Different Brain Regions, Blood Serum, Liver, and Spleen
por: Voelz, Clara, et al.
Publicado: (2021)

Erythropoietin Abrogates Post-Ischemic Activation of the NLRP3, NLRC4, and AIM2 Inflammasomes in Microglia/Macrophages in a TAK1-Dependent Manner
por: Heinisch, Ole, et al.
Publicado: (2021)

α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β(1–42)-stimulated murine astrocytes
por: Ebrahimi, Taraneh, et al.
Publicado: (2018)

Regulation of Inflammasomes by Application of Omega-3 Polyunsaturated Fatty Acids in a Spinal Cord Injury Model
por: Baazm, Maryam, et al.
Publicado: (2021)

Aggregated Tau-PHF6 (VQIVYK) Potentiates NLRP3 Inflammasome Expression and Autophagy in Human Microglial Cells
por: Panda, Chinmaya, et al.
Publicado: (2021)

Presence of The NLRP3 Inflammasome Components in Semen of Varicocele Patients
por: Baazm, Maryam, et al.
Publicado: (2020)

MAPK Is a Mutual Pathway Targeted by Anxiety-Related miRNAs, and E2F5 Is a Putative Target for Anxiolytic miRNAs
por: Amini, Javad, et al.
Publicado: (2023)

Presenilin-1-Derived Circular RNAs: Neglected Epigenetic Regulators with Various Functions in Alzheimer’s Disease
por: Sanadgol, Nima, et al.
Publicado: (2023)

Methylene blue inhibits NLRP3, NLRC4, AIM2, and non-canonical inflammasome activation
por: Ahn, Huijeong, et al.
Publicado: (2017)

Lipocalin-2 Deficiency Diminishes Canonical NLRP3 Inflammasome Formation and IL-1β Production in the Subacute Phase of Spinal Cord Injury
por: Müller, Nina, et al.
Publicado: (2023)

An optimized whole blood assay measuring expression and activity of NLRP3-, NLRC4 and AIM2-inflammasomes
por: Grinstein, L, et al.
Publicado: (2015)

Streptococcus mutans activates the AIM2, NLRP3 and NLRC4 inflammasomes in human THP-1 macrophages
por: Song, Yuri, et al.
Publicado: (2018)

Upregulation of the NLRC4 inflammasome contributes to poor prognosis in glioma patients
por: Lim, Jaejoon, et al.
Publicado: (2019)

Hypoxia Induces Astrocyte-Derived Lipocalin-2 in Ischemic Stroke
por: Ranjbar Taklimie, Fatemeh, et al.
Publicado: (2019)

Astrocytic Nrf2 expression protects spinal cord from oxidative stress following spinal cord injury in a male mouse model
por: Zhao, Weiyi, et al.
Publicado: (2022)

Comparison of infarct volume and behavioral deficit in Wistar Kyoto and spontaneously hypertensive rat after transient occlusion of the middle cerebral artery
por: Garcia, Jorge, et al.
Publicado: (2013)

Taohong siwu decoction attenuates AIM2 and NLRC4 inflammasomes by ameliorates deoxyribonucleic acid damage after ischemic stroke
por: Wang, Ni, et al.
Publicado: (2022)

Riboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity
por: Ahn, Huijeong, et al.
Publicado: (2020)

IgE Immune Complexes Mitigate Eosinophilic Immune Responses through NLRC4 Inflammasome
por: Oylumlu, Ece, et al.
Publicado: (2023)

Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy
por: Yuan, Fang, et al.
Publicado: (2016)

A Fatal Alliance between Microglia, Inflammasomes, and Central Pain
por: Hoffmann, Stefanie, et al.
Publicado: (2020)

Protective effects of erythropoietin against cuprizone-induced oxidative stress and demyelination in the mouse corpus callosum
por: Kashani, Iraj Ragerdi, et al.
Publicado: (2017)

Emerging Concepts about NAIP/NLRC4 Inflammasomes
por: Lage, Silvia Lucena, et al.
Publicado: (2014)

Advances in Understanding Activation and Function of the NLRC4 Inflammasome
por: Sundaram, Balamurugan, et al.
Publicado: (2021)

NLRC4 Inflammasome-Mediated Regulation of Eosinophilic Functions
por: Akkaya, Ilgin, et al.
Publicado: (2021)

Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis
por: Guo, Qingling, et al.
Publicado: (2018)

Association of Tim-3/Gal-9 Axis with NLRC4 Inflammasome in Glioma Malignancy: Tim-3/Gal-9 Induce the NLRC4 Inflammasome
por: Sim, JeongMin, et al.
Publicado: (2022)

LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection
por: Liu, Weiwei, et al.
Publicado: (2017)

Down with doublespeak: NAIP/NLRC4 inflammasomes get specific
por: Aachoui, Youssef, et al.
Publicado: (2016)

A role for the NLRC4 inflammasome in premature rupture of membrane
por: Zhu, Jinming, et al.
Publicado: (2020)

Clostridioides difficile Flagellin Activates the Intracellular NLRC4 Inflammasome
por: Chebly, Hiba, et al.
Publicado: (2022)

Inflammasome-independent functions of AIM2
por: Zhao, Junjie, et al.
Publicado: (2021)

Calpain Inhibitor Calpeptin Alleviates Ischemia/Reperfusion-Induced Acute Kidney Injury via Suppressing AIM2 Inflammasome and Upregulating Klotho Protein
por: Wu, Yong, et al.
Publicado: (2022)

Roles of AIM2 Gene and AIM2 Inflammasome in the Pathogenesis and Treatment of Psoriasis
por: Wang, Jieyi, et al.
Publicado: (2022)

Curcumin activates NLRC4, AIM2, and IFI16 inflammasomes and induces pyroptosis by up-regulated ISG3 transcript factor in acute myeloid leukemia cell lines
por: Zhou, Yuru, et al.
Publicado: (2022)

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome
por: Sutterwala, Fayyaz S., et al.
Publicado: (2007)

The NLRC4 inflammasome requires IRF8-dependent production of NAIPs
por: Lee, Ein, et al.
Publicado: (2018)

SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation
por: Guan, Chenyang, et al.
Publicado: (2021)

Updating the NLRC4 Inflammasome: from Bacterial Infections to Autoimmunity and Cancer
por: Wen, Jiexia, et al.
Publicado: (2021)

The Role of AIM2 Inflammasome in Knee Osteoarthritis
por: Yang, Jiyong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nivb7vdkoajahvmm4698etnsfr