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MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex
MCL1, a BCL2 relative, is critical for the survival of many cells. Its turnover is often tightly controlled through both ubiquitin-dependent and -independent mechanisms of proteasomal degradation. Several cell stress signals, including DNA damage and cell cycle arrest, are known to elicit distinct E...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370232/ https://www.ncbi.nlm.nih.gov/pubmed/32094511 http://dx.doi.org/10.1038/s41418-020-0517-0 |