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Spatio-temporal characterization of the antiviral activity of the XRN1-DCP1/2 aggregation against cytoplasmic RNA viruses to prevent cell death

Host nucleases are implicated in antiviral response through the processing of pathogen-derived nucleic acids. Among many host RNases, decapping enzymes DCP1 and 2, and 5′→3′ exonuclease XRN1, which are components of the RNA decay machinery, have been extensively studied in prokaryotes, plants, and i...

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Detalles Bibliográficos
Autores principales: Ng, Chen Seng, Kasumba, Dacquin M., Fujita, Takashi, Luo, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370233/
https://www.ncbi.nlm.nih.gov/pubmed/32034313
http://dx.doi.org/10.1038/s41418-020-0509-0