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Tumors Resistant to Checkpoint Inhibitors Can Become Sensitive after Treatment with Vascular Disrupting Agents
Immune therapy improves cancer outcomes, yet many patients do not respond. This pre-clinical study investigated whether vascular disrupting agents (VDAs) could convert an immune unresponsive tumor into a responder. CDF1 mice, with 200 mm(3) C3H mammary carcinomas in the right rear foot, were intrape...
Autores principales: | Horsman, Michael R., Wittenborn, Thomas R., Nielsen, Patricia S., Elming, Pernille B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370297/ https://www.ncbi.nlm.nih.gov/pubmed/32640548 http://dx.doi.org/10.3390/ijms21134778 |
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