Cargando…
Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening
Tissue-resident macrophages are key players in inflammatory processes, and their activation and functionality are crucial in health and disease. Numerous diseases are associated with alterations in homeostasis or dysregulation of the innate immune system, including allergic reactions, autoimmune dis...
Autores principales: | Gutbier, Simon, Wanke, Florian, Dahm, Nadine, Rümmelin, Anna, Zimmermann, Silke, Christensen, Klaus, Köchl, Fabian, Rautanen, Anna, Hatje, Klas, Geering, Barbara, Zhang, Jitao David, Britschgi, Markus, Cowley, Sally A., Patsch, Christoph |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370446/ https://www.ncbi.nlm.nih.gov/pubmed/32645954 http://dx.doi.org/10.3390/ijms21134808 |
Ejemplares similares
-
Alzheimer’s Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia
por: Reich, Marvin, et al.
Publicado: (2021) -
Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages
por: Wanke, Florian, et al.
Publicado: (2021) -
Honing the Double-Edged Sword: Improving Human iPSC-Microglia Models
por: Hedegaard, Anne, et al.
Publicado: (2020) -
Generation of an hiPSC-Derived Co-Culture System to Assess the Effects of Neuroinflammation on Blood–Brain Barrier Integrity
por: Bull, Daniel, et al.
Publicado: (2022) -
iPSC for modeling neurodegenerative disorders
por: Valadez-Barba, Valeria, et al.
Publicado: (2020)