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Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals

Meningiomas are the most common primary intracranial tumors, but treatment options for meningioma patients are limited due to incomplete understanding of tumor biology. A small percentage of meningiomas harbor somatic variants in the Hedgehog pathway, a conserved gene expression program that is esse...

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Detalles Bibliográficos
Autores principales: Findakly, Sarah, Choudhury, Abrar, Daggubati, Vikas, Pekmezci, Melike, Lang, Ursula E., Raleigh, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370519/
https://www.ncbi.nlm.nih.gov/pubmed/32690089
http://dx.doi.org/10.1186/s40478-020-00994-7