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Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals
Meningiomas are the most common primary intracranial tumors, but treatment options for meningioma patients are limited due to incomplete understanding of tumor biology. A small percentage of meningiomas harbor somatic variants in the Hedgehog pathway, a conserved gene expression program that is esse...
Autores principales: | Findakly, Sarah, Choudhury, Abrar, Daggubati, Vikas, Pekmezci, Melike, Lang, Ursula E., Raleigh, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370519/ https://www.ncbi.nlm.nih.gov/pubmed/32690089 http://dx.doi.org/10.1186/s40478-020-00994-7 |
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