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Analysis of Risk Factors for Cognitive Dysfunction in Disabled Elderly Patients in Chengdu, China

BACKGROUND: With the aging population comes an increase in functional disability that leads to dependency and institutionalization, as well as social, medical, and economic challenges. This study aimed to classify and assess the factors affecting cognitive deficits in disabled elderly people. MATERI...

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Autores principales: Chen, Xiaoyan, Zhang, Ying, Hou, Lisha, Shen, Yanjiao, Li, Jianqun, Dong, Birong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370575/
https://www.ncbi.nlm.nih.gov/pubmed/32684617
http://dx.doi.org/10.12659/MSM.923590
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author Chen, Xiaoyan
Zhang, Ying
Hou, Lisha
Shen, Yanjiao
Li, Jianqun
Dong, Birong
author_facet Chen, Xiaoyan
Zhang, Ying
Hou, Lisha
Shen, Yanjiao
Li, Jianqun
Dong, Birong
author_sort Chen, Xiaoyan
collection PubMed
description BACKGROUND: With the aging population comes an increase in functional disability that leads to dependency and institutionalization, as well as social, medical, and economic challenges. This study aimed to classify and assess the factors affecting cognitive deficits in disabled elderly people. MATERIAL/METHODS: Disabled patients ≥60 years old were assessed by face-to-face cross-sectional surveys, which were conducted using advanced peer-to-peer software. The ability to perform daily life tasks was assessed using the Modified Barthel Index. Cognitive function was evaluated with the Mini-cognitive assessment instrument. Using these surveys, 9471 individuals were included in this study. The rank-sum test was used to investigate differences between groups. Disordered multi-class logistic regression was used to correct related confounding factors for multivariate analysis. RESULTS: The ratios of normal cognitive function, cognitive impairment, and dementia were 3.71%, 38.59%, and 57.70%, respectively. The univariate analysis and multivariate analysis showed that older individuals (≥80 years), women, illiterate individuals, and lonely persons were more prone to dementia. Moreover, a history of hypertension, diabetes, osteoporosis, and fractures were significantly associated with dementia. CONCLUSIONS: The proportion of dementia in the elderly disabled patients is very high (57.7%) in Chengdu City. Age (≥80 years), female sex, education level (illiterate individuals), living conditions, and chronic disease were closely correlated with cognitive functions.
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spelling pubmed-73705752020-08-03 Analysis of Risk Factors for Cognitive Dysfunction in Disabled Elderly Patients in Chengdu, China Chen, Xiaoyan Zhang, Ying Hou, Lisha Shen, Yanjiao Li, Jianqun Dong, Birong Med Sci Monit Clinical Research BACKGROUND: With the aging population comes an increase in functional disability that leads to dependency and institutionalization, as well as social, medical, and economic challenges. This study aimed to classify and assess the factors affecting cognitive deficits in disabled elderly people. MATERIAL/METHODS: Disabled patients ≥60 years old were assessed by face-to-face cross-sectional surveys, which were conducted using advanced peer-to-peer software. The ability to perform daily life tasks was assessed using the Modified Barthel Index. Cognitive function was evaluated with the Mini-cognitive assessment instrument. Using these surveys, 9471 individuals were included in this study. The rank-sum test was used to investigate differences between groups. Disordered multi-class logistic regression was used to correct related confounding factors for multivariate analysis. RESULTS: The ratios of normal cognitive function, cognitive impairment, and dementia were 3.71%, 38.59%, and 57.70%, respectively. The univariate analysis and multivariate analysis showed that older individuals (≥80 years), women, illiterate individuals, and lonely persons were more prone to dementia. Moreover, a history of hypertension, diabetes, osteoporosis, and fractures were significantly associated with dementia. CONCLUSIONS: The proportion of dementia in the elderly disabled patients is very high (57.7%) in Chengdu City. Age (≥80 years), female sex, education level (illiterate individuals), living conditions, and chronic disease were closely correlated with cognitive functions. International Scientific Literature, Inc. 2020-07-09 /pmc/articles/PMC7370575/ /pubmed/32684617 http://dx.doi.org/10.12659/MSM.923590 Text en © Med Sci Monit, 2020 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Chen, Xiaoyan
Zhang, Ying
Hou, Lisha
Shen, Yanjiao
Li, Jianqun
Dong, Birong
Analysis of Risk Factors for Cognitive Dysfunction in Disabled Elderly Patients in Chengdu, China
title Analysis of Risk Factors for Cognitive Dysfunction in Disabled Elderly Patients in Chengdu, China
title_full Analysis of Risk Factors for Cognitive Dysfunction in Disabled Elderly Patients in Chengdu, China
title_fullStr Analysis of Risk Factors for Cognitive Dysfunction in Disabled Elderly Patients in Chengdu, China
title_full_unstemmed Analysis of Risk Factors for Cognitive Dysfunction in Disabled Elderly Patients in Chengdu, China
title_short Analysis of Risk Factors for Cognitive Dysfunction in Disabled Elderly Patients in Chengdu, China
title_sort analysis of risk factors for cognitive dysfunction in disabled elderly patients in chengdu, china
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370575/
https://www.ncbi.nlm.nih.gov/pubmed/32684617
http://dx.doi.org/10.12659/MSM.923590
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