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High-Dose Methotrexate in Pediatric Acute Lymphoblastic Leukemia: Predictors of Delayed Clearance and the Effect of Increased Hydration Rate on Methotrexate Clearance

Objectives High-dose methotrexate (HDMTX) is an important chemotherapeutic agent in the treatment of many cancers. Identification of the predictors of poor clearance during HDMTX infusions could advance the introduction of improved supportive care to prevent toxicities and reduce hospital length of...

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Detalles Bibliográficos
Autores principales:	Chen, Aaron R, Wang, YunZu M, Lin, Mark, Kuo, Dennis J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cureus 2020
Materias:	Pediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370657/ https://www.ncbi.nlm.nih.gov/pubmed/32699674 http://dx.doi.org/10.7759/cureus.8674

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