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Autophagy regulates the localization and degradation of p16(INK4a)
The tumor suppressor protein p16(INK4a) (p16) is a well‐established hallmark of aging that induces cellular senescence in response to stress. Previous studies have focused primarily on p16 regulation at the transcriptional level; comparatively little is known about the protein's intracellular l...
Autores principales: | Coryell, Philip R., Goraya, Supreet K., Griffin, Katherine A., Redick, Margaret A., Sisk, Samuel R., Purvis, Jeremy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370706/ https://www.ncbi.nlm.nih.gov/pubmed/32662244 http://dx.doi.org/10.1111/acel.13171 |
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