Utilizing CRISPR/Cas9 technology to prepare lymphoblastoid cell lines harboring genetic mutations for generating quality control materials in genetic testing

BACKGROUND: To meet the requirements of the rapidly progressing genetic testing technologies in clinical laboratories, assuring the quality of genetic tests by utilizing appropriate quality control materials is of paramount importance. The CRISPR/Cas9 technology was used to prepare quality control m...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Li, Rui, Zhang, Runling, Peng, Rongxue, Chen, Kun, Gao, Peng, Zhang, Jiawei, Zhang, Rui, Li, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370731/
https://www.ncbi.nlm.nih.gov/pubmed/32118319
http://dx.doi.org/10.1002/jcla.23256

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