Cargando…

Geriatric fragility fractures are associated with a human skeletal stem cell defect

Fragility fractures have a limited capacity to regenerate, and impaired fracture healing is a leading cause of morbidity in the elderly. The recent identification of a highly purified bona fide human skeletal stem cell (hSSC) and its committed downstream progenitor cell populations provides an oppor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ambrosi, Thomas H., Goodnough, L. Henry, Steininger, Holly M., Hoover, Malachia Y., Kim, Emiley, Koepke, Lauren S., Marecic, Owen, Zhao, Liming, Seita, Jun, Bishop, Julius A., Gardner, Michael J., Chan, Charles K. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370785/ https://www.ncbi.nlm.nih.gov/pubmed/32537886 http://dx.doi.org/10.1111/acel.13164

Ejemplares similares

Cross-species comparisons reveal resistance of human skeletal stem cells to inhibition by non-steroidal anti-inflammatory drugs
por: Goodnough, L. Henry, et al.
Publicado: (2022)

Distinct skeletal stem cell types orchestrate long bone skeletogenesis
por: Ambrosi, Thomas H, et al.
Publicado: (2021)

Delayed Union of a Diaphyseal Forearm Fracture Associated With Impaired Osteogenic Differentiation of Prospectively Isolated Human Skeletal Stem Cells
por: Goodnough, L Henry, et al.
Publicado: (2020)

Sexually dimorphic estrogen sensing in skeletal stem cells controls skeletal regeneration
por: Andrew, Tom W., et al.
Publicado: (2022)

Abstract 58: Multimodal manipulation of the Skeletal Stem Cell for Articular Cartilage Regeneration
por: Murphy, Matthew P., et al.
Publicado: (2018)

Human skeletal stem cell aging
por: Ambrosi, Thomas H., et al.
Publicado: (2020)

A Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue
por: Zhao, Liming, et al.
Publicado: (2023)

Skeletal stem cells and their contribution to skeletal fragility: senescence and rejuvenation
por: Aldahmash, Abdullah
Publicado: (2015)

Skeletal Fragility in Type 2 Diabetes Mellitus
por: Starup-Linde, Jakob, et al.
Publicado: (2018)

Antibiotic resistance: still a cause of concern?
por: DeBaun, Malcolm R., et al.
Publicado: (2021)

Fragility Fracture Care: An Urgent Need to Implement the Integrated Model of Geriatric Care
por: Lim, Jae-Young
Publicado: (2019)

Significant Loss of Skeletal Muscle Mass Occurs After Femoral Fragility Fracture
por: Miller, Aspen, et al.
Publicado: (2022)

Vascular deficits contributing to skeletal fragility in type 1 diabetes
por: Draghici, Adina E., et al.
Publicado: (2023)

Bone fragility in patients affected by congenital diseases non skeletal in origin
por: Masi, L., et al.
Publicado: (2021)

Circuit level defects in the developing neocortex of fragile X mice
por: Gonçalves, J. Tiago, et al.
Publicado: (2013)

Geriatric Vascular Surgery: Time to Build Optimal Resources for the Perioperative Care of Elderly and Fragile Vascular Patients
por: Min, Seung-Kee
Publicado: (2021)

Risk of Contralateral Hip Fracture Following Initial Hip Fracture Among Geriatric Fragility Fracture Patients
por: Ratnasamy, Philip P., et al.
Publicado: (2023)

Evaluation of the geriatric co-management for patients with fragility fractures of the proximal femur (Geriatric Fracture Centre (GFC) concept): protocol for a prospective multicentre cohort study
por: Joeris, Alexander, et al.
Publicado: (2017)

Impact on periosteal vasculature after dual plating of the distal femur: a cadaveric study
por: Chen, Michael J., et al.
Publicado: (2021)

Racial differences in skeletal fragility but not osteoarthritis among women and men with cerebral palsy()
por: Whitney, Daniel G.
Publicado: (2019)

Disparities in Total Hip Arthroplasty Versus Hemiarthroplasty in the Management of Geriatric Femoral Neck Fractures
por: Dangelmajer, Sean, et al.
Publicado: (2017)

Outcomes and Impact of Fragility Fracture among Geriatrics Patients who Underwent Hip Surgery in Hospital Kuala Lumpur
por: Lim, HT, et al.
Publicado: (2022)

Del1 Is a Growth Factor for Skeletal Progenitor Cells in the Fracture Callus
por: Sun, Yuxi, et al.
Publicado: (2023)

Geriatric assessment for oncologists
por: Korc-Grodzicki, Beatriz, et al.
Publicado: (2015)

Curvafix: A novel implant for pelvic fragility fractures
por: Miller, Hannah S., et al.
Publicado: (2022)

Muscle-skeletal fragility: data about elderly people who live in RSA in Calabria
por: Bartoletti, M G, et al.
Publicado: (2010)

Raloxifene Prevents Skeletal Fragility in Adult Female Zucker Diabetic Sprague-Dawley Rats
por: Hill Gallant, Kathleen M., et al.
Publicado: (2014)

PEAK1 Acts as a Molecular Switch to Regulate Context-Dependent TGFβ Responses in Breast Cancer
por: Agajanian, Megan, et al.
Publicado: (2015)

Schnurri-3 inhibition rescues skeletal fragility and vascular skeletal stem cell niche pathology in a mouse model of osteogenesis imperfecta
por: Xu, Ren, et al.
Publicado: (2023)

An ARHGAP25 variant links aberrant Rac1 function to early‐onset skeletal fragility
por: Mäkitie, Riikka E., et al.
Publicado: (2021)

Cardiovascular benefits and risks associated with calcium, vitamin D, and antiresorptive therapy in the management of skeletal fragility
por: Kittithaworn, Annop, et al.
Publicado: (2023)

Role of Body Composition in the Prediction of Skeletal Fragility Induced by Hormone Deprivation Therapies in Cancer Patients
por: Dalla Volta, Alberto, et al.
Publicado: (2023)

Fragile
por: CERN Press Office. Geneva
Publicado: (1975)

Abstract QS34: Prospective Isolation of a Functional Human Cartilage Progenitor Capable of Forming Hyaline Cartilage In Vivo
por: Koepke, Lauren
Publicado: (2018)

Argonaute2 Suppresses Drosophila Fragile X Expression Preventing Neurogenesis and Oogenesis Defects
por: Pepper, Anita S.-R., et al.
Publicado: (2009)

ESCRT-III Membrane Trafficking Misregulation Contributes To Fragile X Syndrome Synaptic Defects
por: Vita, Dominic J., et al.
Publicado: (2017)

Autism and heritable bone fragility: A true association?
por: Balasubramanian, Meena, et al.
Publicado: (2018)

Skeletal Dysplasias Caused by Sulfation Defects
por: Paganini, Chiara, et al.
Publicado: (2020)

Optimizing Delivery of Therapeutic Growth Factors for Bone and Cartilage Regeneration
por: Takematsu, Eri, et al.
Publicado: (2023)

Rare Copy Number Variants in Array-Based Comparative Genomic Hybridization in Early-Onset Skeletal Fragility
por: Costantini, Alice, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rf9dllvgeeij9qhm0mbgs096jf