Paternal age in rhesus macaques is positively associated with germline mutation accumulation but not with measures of offspring sociability

Mutation is the ultimate source of all genetic novelty and the cause of heritable genetic disorders. Mutational burden has been linked to complex disease, including neurodevelopmental disorders such as schizophrenia and autism. The rate of mutation is a fundamental genomic parameter and direct estim...

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Detalles Bibliográficos
Autores principales: Wang, Richard J., Thomas, Gregg W.C., Raveendran, Muthuswamy, Harris, R. Alan, Doddapaneni, Harshavardhan, Muzny, Donna M., Capitanio, John P., Radivojac, Predrag, Rogers, Jeffrey, Hahn, Matthew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370888/
https://www.ncbi.nlm.nih.gov/pubmed/32461224
http://dx.doi.org/10.1101/gr.255174.119

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