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Inhibition of miR-181a promotes midbrain neuronal growth through a Smad1/5-dependent mechanism: implications for Parkinson’s disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease, and is characterized by the progressive degeneration of nigrostriatal dopaminergic (DA) neurons. Current PD treatments are symptomatic, wear off over time and do not protect against DA neuronal loss. Finding a way to re-gr...

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Detalles Bibliográficos
Autores principales: Hegarty, Shane V., Sullivan, Aideen M., O’Keeffe, Gerard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371012/
https://www.ncbi.nlm.nih.gov/pubmed/32714583
http://dx.doi.org/10.1042/NS20170181